Mechanism of Action

Diclofenac works by inhibiting cyclooxygenase (COX-1 & COX-2) enzymes, reducing the production of prostaglandins responsible for pain and inflammation.

➡️ Result: Pain relief + reduced swelling + anti-inflammatory effect

Indications

• Post-operative pain
• Musculoskeletal pain (sprains, strains)
• Renal colic
• Arthritis (RA, OA, ankylosing spondylitis)
• Acute gout attacks
• Trauma-related pain

Key Benefits

• Fast-acting injectable pain relief
• Effective for moderate to severe pain
• Reduces inflammation and swelling
• Useful when oral NSAIDs are not feasible

Dosage & Administration

• Typically 75 mg IM or slow IV infusion, as prescribed
• Maximum dose: usually 150 mg/day
• Administered by healthcare professionals only

Safety Information

• Common side effects:

• • Injection site pain
  • Nausea, vomiting
  • Gastric irritation

• Serious risks:

• • GI bleeding
  • Kidney impairment
  • Cardiovascular risks

Precautions

• Avoid in:

• • Peptic ulcer disease
  • Severe kidney/liver disease
  • NSAID hypersensitivity

• Use cautiously in elderly and cardiac patients
• Not recommended in third trimester of pregnancy

Contraindications

• History of NSAID allergy
• Active gastrointestinal bleeding
• Severe heart failure

Storage

• Store below 25°C
• Protect from light

Quality Assurance

• Manufactured under WHO-GMP certified standards
• Sterile, hospital-grade injectable formulation

Important Note

This injection should be used only under medical supervision.
Improper use may lead to serious complications like gastric bleeding or kidney damage.

Conclusion

Diclofenac Sodium Injection 75 mg is a powerful and fast-acting analgesic widely used in clinical settings for acute pain management, offering reliable relief when administered appropriately.